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CBmeter- a new medical device for early screening of metabolic diseases

dc.contributor.authorGuarino, Maria Pedro
dc.contributor.authorBrito, Gabriel
dc.contributor.authorLages, Marlene
dc.contributor.authorFonseca-Pinto, Rui
dc.contributor.authorLopes, Nuno Vieira
dc.date.accessioned2018-09-24T07:48:55Z
dc.date.available2018-09-24T07:48:55Z
dc.date.issued2018-05
dc.description.abstractType 2 diabetes mellitus (T2DM) is a highly prevalent disease worldwide which is asymptomatic in about 44% of patients being critical to search for new ways of early diagnosis. Recent studies have demonstrated that the etiology of this disease may be associated with alterations in the function of the carotid body (CB), a chemosensor organ located within the bifurcation of the carotid artery. In animal models of metabolic syndrome it was observed that the CBs are overactivated, underlying diseases such as obesity, hypertension and T2DM. This discovery provided a new paradigm in the neuroendocrinology field, suggesting that diagnostic function of the CBs has predictive value for the development of metabolic diseases. Despite this fact, it is not common in clinical practice to look at the CBs as organs associated with endocrine dysfunction and we believe this is probably due to the nonexistence of a user-friendly, portable medical device that diagnosis the function of the CBs.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.issn1472-6963
dc.identifier.urihttp://hdl.handle.net/10400.8/3544
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherBMC Health Services Researchpt_PT
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/pt_PT
dc.titleCBmeter- a new medical device for early screening of metabolic diseasespt_PT
dc.typeconference object
dspace.entity.typePublication
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/9876 - Politécnicos/SAICT-POL%2F23278%2F2016/PT
oaire.citation.conferencePlaceLeiriapt_PT
oaire.citation.startPage684pt_PT
oaire.citation.titleProceedings of the 4th IPLeiria’s International Health Congresspt_PT
oaire.citation.volumeVolume 18 Supplement 2pt_PT
oaire.fundingStream9876 - Politécnicos
person.familyNameGuarino
person.familyNameCorreia-Brito
person.familyNameLages
person.familyNameFonseca-Pinto
person.familyNameVieira Lopes
person.givenNameMaria Pedro
person.givenNameGabriel
person.givenNameMarlene
person.givenNameRui
person.givenNameNuno
person.identifier.ciencia-idF21A-BD01-2D52
person.identifier.ciencia-idC613-4639-10A8
person.identifier.ciencia-id681D-C547-B184
person.identifier.ciencia-idE117-67AC-0B45
person.identifier.orcid0000-0001-6079-1105
person.identifier.orcid0000-0001-5077-4520
person.identifier.orcid0000-0002-7389-6368
person.identifier.orcid0000-0001-6774-5363
person.identifier.orcid0000-0002-2232-1839
person.identifier.ridB-5594-2015
person.identifier.ridK-9449-2014
person.identifier.scopus-author-id56348477000
person.identifier.scopus-author-id57206777195
person.identifier.scopus-author-id26039086400
person.identifier.scopus-author-id26031536700
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.rightsopenAccesspt_PT
rcaap.typeconferenceObjectpt_PT
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