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Risk assessment of trihalomethanes exposure by consumption of IV gamma products: Evidences from a Portuguese regional survey

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dc.contributor.authorSimões, Cátia
dc.contributor.authorMendes, Susana
dc.contributor.authorMartins, Alice
dc.contributor.authorGil, Maria M.
dc.date.accessioned2021-08-23T12:40:04Z
dc.date.available2021-08-23T12:40:04Z
dc.date.issued2020
dc.descriptionAuthors are very grateful to FCT (Fundação para a Ciência e a Tecnologia) for the financial support of this work through the projects UID/MAR/04292/2019, attributed to MARE - Marine and Environmental Sciences Centre, Politécnico de Leiria, Portugal. This work was also partially funded by the Integrated Programme of SR&TD “SmartBioR” (reference Centro-01-0145-FEDER-000018) co-funded by Centro 2020 program, Portugal2020, European Union, through the European Regional Development Fund. We also acknowledge Engª Georgina Sarmento and Dr. Ana Cruz, from LAIST, for lab facilities and technical support related to THMs analysis.
dc.description.abstractDue to the current demand for healthier food, the IV gamma products industry has grown over the years. Additionally, it is well known that chlorine is a disinfectant largely used in this industry. However, the risk assessment associated with the formation of carcinogenic by-products from this halogenated disinfection has not been widely studied. The aim of this study was to assess the trihalomethanes (THMs) exposure through the consumption of IV gamma products, more specifically, salad mixes, and potential health risk in Portuguese population using a deterministic method. The quantification of THMs in salad mixes from the most representative Portuguese brands was performed by gas chromatography coupled to mass spectrometry (GC–MS). The THMs exposures were estimated by combining the THMs concentration data with a ready-to-eat salad mix consumption survey (case study applied in the Lisboa e Vale do Tejo area; n = 271). The concentration of THMs in all samples was below the limit of quantification of the equipment (1 μg/L), and this limit was used for the evaluation of the exposure. It was found that it is very small for the consumption pattern of these products in the studied population categories, suggesting that there is no risk for consumers due to the halogenated disinfection process. The highest estimated daily exposure was 7,65X10−5 mg/ kg bw/ week, which corresponds to a person who consumes such products daily.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationCátia Simões, Susana Mendes, Alice Martins, Maria M. Gil, Risk assessment of trihalomethanes exposure by consumption of IV gamma products: Evidences from a Portuguese regional survey, Toxicology Reports, Volume 7, 2020, Pages 288-295, ISSN 2214-7500, https://doi.org/10.1016/j.toxrep.2020.01.019.pt_PT
dc.identifier.doi10.1016/j.toxrep.2020.01.019pt_PT
dc.identifier.issn2214-7500
dc.identifier.urihttp://hdl.handle.net/10400.8/6138
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherElsevierpt_PT
dc.relationMARE - Marine and Environmental Sciences Centre
dc.relation.publisherversionhttps://www.sciencedirect.com/science/article/pii/S221475001930589Xpt_PT
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/pt_PT
dc.subjectTrihalomethanespt_PT
dc.subjectFood safetypt_PT
dc.subjectExposurept_PT
dc.subjectChlorine disinfectionpt_PT
dc.subjectReady-to-eat vegetablespt_PT
dc.subjectIV gamma productspt_PT
dc.titleRisk assessment of trihalomethanes exposure by consumption of IV gamma products: Evidences from a Portuguese regional surveypt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.awardNumberUID/MAR/04292/2019
oaire.awardTitleMARE - Marine and Environmental Sciences Centre
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UID%2FMAR%2F04292%2F2019/PT
oaire.citation.endPage295pt_PT
oaire.citation.startPage288pt_PT
oaire.citation.titleToxicology Reportspt_PT
oaire.citation.volume7pt_PT
oaire.fundingStream6817 - DCRRNI ID
person.familyNameMendes
person.familyNameMartins
person.familyNameGil
person.givenNameSusana
person.givenNameAlice
person.givenNameMaria M
person.identifier322266
person.identifier.ciencia-id4514-12E2-1FD9
person.identifier.ciencia-idDA19-728A-9BC8
person.identifier.ciencia-id7313-A289-DF48
person.identifier.orcid0000-0001-9681-3169
person.identifier.orcid0000-0002-0542-2662
person.identifier.orcid0000-0002-8008-9839
person.identifier.ridO-4858-2015
person.identifier.scopus-author-id33568138000
person.identifier.scopus-author-id56013514200
person.identifier.scopus-author-id12785024700
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
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