Computational Modelling on Bone Tissue Regeneration: Towards the translation for clinical practice

Publications

Mechanical properties assessment for TPMS based scaffolds using homogenization methods

Publication . Pinheiro, J.; Castro, A. P. G.; Ruben, R. B.; Guedes, J. M.; Fernandes, P. R.

The combination of computational methods with recent 3D printing technologies allows for the control of scaffolds microstructure, in order to obtain application-driven mechanical properties. Lately, geometries obtained using triply periodic minimal surfaces (TPMS) have been used to design porosity-controlled scaffolds for bone tissue engineering. The objective for this work is to assess the properties of TPMS scaffolds obtained using Schwartz P, Schwartz D and Gyroid, with different porosity levels. These properties are computed by an asymptotic homogenization method to obtain the effective permeability and stiffness. Results show that the obtained properties compare well with the properties of bone scaffolds presented in literature and obtained using different means.

2020Conference paper

Open access

Keywords

Engenharia de Tecidos,Mecanobiologia Computacional,Mecânica do Tecido Ósseo,Substitutos Ósseos, Engineering and technology ,Engineering and technology/Industrial biotechnology

Funding agency

Fundação para a Ciência e a Tecnologia, I.P.

Funding programme

Projetos de Investigação Científica e Desenvolvimento Tecnológico - 2014

Funding Award Number

PTDC/BBB-BMC/5655/2014