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Mineralization of Sialoliths Investigated by Ex Vivo and In Vivo X-ray Computed Tomography

2019-02Journal article Open access
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dc.contributor.authorNolasco, Pedro
dc.contributor.authorCoelho, Paulo V.
dc.contributor.authorCoelho, Carla
dc.contributor.authorAngelo, David F.
dc.contributor.authorDias, J. R.
dc.contributor.authorAlves, Nuno M.
dc.contributor.authorMaurício, António
dc.contributor.authorPereira, Manuel F.C.
dc.contributor.authorMatos, António P. Alves de
dc.contributor.authorMartins, Raul C.
dc.contributor.authorCarvalho, Patrícia A.
dc.date.accessioned2023-06-13T09:10:38Z
dc.date.available2023-06-13T09:10:38Z
dc.date.issued2019-02
dc.description.abstractThe fraction of organic matter present affects the fragmentation behavior of sialoliths; thus, pretherapeutic information on the degree of mineralization is relevant for a correct selection of lithotripsy procedures. This work proposes a methodology for in vivo characterization of salivary calculi in the pretherapeutic context. Sialoliths were characterized in detail by X-ray computed microtomography (μCT) in combination with atomic emission spectroscopy, Fourier transform infrared spectroscopy, X-ray diffraction, scanning electron microscopy, and transmission electron microscopy. Correlative analysis of the same specimens was performed by in vivo and ex vivo helical computed tomography (HCT) and ex vivo μCT. The mineral matter in the sialoliths consisted essentially of apatite (89 vol%) and whitlockite (11 vol%) with average density of 1.8 g/cm3. In hydrated conditions, the mineral mass prevailed with 53 ± 13 wt%, whereas the organic matter, with a density of 1.2 g/cm3, occupied 65 ± 10% of the sialoliths' volume. A quantitative relation between sialoliths mineral density and X-ray attenuation is proposed for both HCT and μCT.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationNolasco, P., Coelho, P., Coelho, C., Angelo, D., Dias, J., Alves, N., . . . Carvalho, P. (2019). Mineralization of Sialoliths Investigated by Ex Vivo and In Vivo X-ray Computed Tomography. Microscopy and Microanalysis, 25(1), 151-163. doi:10.1017/S1431927618016124pt_PT
dc.identifier.doihttps://doi.org/10.1017/S1431927618016124pt_PT
dc.identifier.eissn1435-8115
dc.identifier.issn1431-9276
dc.identifier.pmid30714561
dc.identifier.urihttp://hdl.handle.net/10400.8/8580
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherOxford University Presspt_PT
dc.relation.publisherversionhttps://www.cambridge.org/core/journals/microscopy-and-microanalysis/article/mineralization-of-sialoliths-investigated-by-ex-vivo-and-in-vivo-xray-computed-tomography/63B5EC4A9721F217C4F4A8E53E9590D7pt_PT
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/pt_PT
dc.subjectX-ray attenuationpt_PT
dc.subjectCompositionpt_PT
dc.subjectComputed tomographypt_PT
dc.subjectLithotripsy efficiencypt_PT
dc.subjectLithotripsy methodspt_PT
dc.subjectMultimodal managementpt_PT
dc.subjectSialolithspt_PT
dc.titleMineralization of Sialoliths Investigated by Ex Vivo and In Vivo X-ray Computed Tomographypt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage163pt_PT
oaire.citation.issue1pt_PT
oaire.citation.startPage151pt_PT
oaire.citation.titleMicroscopy and Microanalysispt_PT
oaire.citation.volume25pt_PT
person.familyNameAlves
person.givenNameNuno
person.identifier452149
person.identifier.ciencia-id311E-1559-8F6C
person.identifier.orcid0000-0002-5016-0868
person.identifier.ridN-4073-2013
person.identifier.scopus-author-id7006403383
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublicationbbd46a74-b77e-4539-a5fe-62ee95cdc4fa
relation.isAuthorOfPublication.latestForDiscoverybbd46a74-b77e-4539-a5fe-62ee95cdc4fa

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