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Additive manufacturing techniques for scaffold-based cartilage tissue engineering

2013-09Artigo científico Acesso restrito
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datacite.subject.fosEngenharia e Tecnologia::Engenharia dos Materiais
datacite.subject.sdg03:Saúde de Qualidade
datacite.subject.sdg09:Indústria, Inovação e Infraestruturas
datacite.subject.sdg12:Produção e Consumo Sustentáveis
dc.contributor.authorCaseiro, Ana Rita
dc.contributor.authorAlmeida, Henrique A.
dc.contributor.authorBártolo, Paulo J.
dc.date.accessioned2026-03-09T15:00:06Z
dc.date.available2026-03-09T15:00:06Z
dc.date.issued2013-09
dc.description.abstractArticular cartilage damage is of great concern as it creates chronic pain and reduction of joint movement, leading to osteoarthritis. In current treatments, the resulting healing tissues lack structural organisation of cartilage and consequently have inferior mechanical properties when compared to native cartilage, therefore being prone to failure. Tissue engineering has long worked on cartilage regeneration and several requirements have been identified for the engineered structures to meet the desired function, by combining biodegradable and biocompatible materials, cells and growth factors, aiming at the production of biological structures closely resembling the native tissue.Within the scaffold based techniques for cartilage tissue production, conventional methods have shown limitations, especially regarding the control over the microstructure and repeatability of the produced constructs. Therefore, additive manufacturing techniques grew popular, allowing for a high level of control over the internal scaffold architecture and external shape of the construct, as well as guaranteeing its reproducibility.eng
dc.description.sponsorshipThis research was supported by the Portuguese Foundation for Science and Technology through a Strategic Project – UI-4044-2011-2012 (Pest-OE/EME/UI4044/2011). Authors also acknowledge the support of the European Commission through the Project “Hydrozone – Bioactivated hierarchical hydrogels as zonal implants for articular regeneration” (FP7-NMP-2012-Large 6, NNP.2012.2.2-1).
dc.identifier.citationSantos, A. R. C., Almeida, H. A., & Bártolo, P. J. (2013). Additive manufacturing techniques for scaffold-based cartilage tissue engineering: A review on various additive manufacturing technologies in generating scaffolds for cartilage tissue engineering. Virtual and Physical Prototyping, 8(3), 175–186. https://doi.org/10.1080/17452759.2013.838825
dc.identifier.doi10.1080/17452759.2013.838825
dc.identifier.issn1745-2759
dc.identifier.issn1745-2767
dc.identifier.urihttp://hdl.handle.net/10400.8/15811
dc.language.isoeng
dc.peerreviewedyes
dc.publisherTaylor and Francis
dc.relationStrategic Project - UI 4044 - 2011-2012
dc.relation.hasversionhttps://www.tandfonline.com/doi/full/10.1080/17452759.2013.838825
dc.relation.ispartofVirtual and Physical Prototyping
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/
dc.subjectBiomanufacturing
dc.subjectBiomaterials
dc.subjectBioengineering
dc.titleAdditive manufacturing techniques for scaffold-based cartilage tissue engineeringeng
dc.title.alternativeA review on various additive manufacturing technologies in generating scaffolds for cartilage tissue engineeringeng
dc.typejournal article
dspace.entity.typePublication
oaire.awardNumberPEst-OE/EME/UI4044/2011
oaire.awardTitleStrategic Project - UI 4044 - 2011-2012
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/PEst-OE%2FEME%2FUI4044%2F2011/PT
oaire.citation.endPage186
oaire.citation.issue3
oaire.citation.startPage175
oaire.citation.titleVirtual and Physical Prototyping
oaire.citation.volume8
oaire.fundingStream6817 - DCRRNI ID
oaire.versionhttp://purl.org/coar/version/c_970fb48d4fbd8a85
person.familyNameCaseiro Santos
person.familyNameAlmeida
person.familyNameBartolo
person.givenNameAna Rita
person.givenNameHenrique de Amorim
person.givenNamePaulo
person.identifier46395
person.identifier203086
person.identifier.ciencia-id8F1D-4370-84BE
person.identifier.ciencia-id5810-9BF9-4522
person.identifier.orcid0000-0002-1143-2461
person.identifier.orcid0000-0002-1367-2290
person.identifier.orcid0000-0003-3683-726X
person.identifier.ridD-6275-2012
person.identifier.ridF-2421-2013
person.identifier.scopus-author-id55938867800
person.identifier.scopus-author-id6603353041
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
relation.isAuthorOfPublication09f3013f-81ac-4c52-bdf6-2a3dc83f348f
relation.isAuthorOfPublicationf3bfdd6a-e959-4e13-8a20-fb1b286a3dd0
relation.isAuthorOfPublicationab44d1ae-46d0-45c2-b19f-200024b5a990
relation.isAuthorOfPublication.latestForDiscovery09f3013f-81ac-4c52-bdf6-2a3dc83f348f
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