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Biological Treatments for Temporomandibular Joint Disc Disorders: Strategies in Tissue Engineering

dc.contributor.authorTrindade, Daniela
dc.contributor.authorCordeiro, Rachel
dc.contributor.authorJosé, Henrique Cardoso
dc.contributor.authorDF, Angelo
dc.contributor.authorAlves, Nuno
dc.contributor.authorMoura, Carla
dc.date.accessioned2023-04-13T15:06:56Z
dc.date.available2023-04-13T15:06:56Z
dc.date.issued2021-06-23
dc.description.abstractThe temporomandibular joint (TMJ) is an important structure for the masticatory system and the pathologies associated with it affect a large part of the population and impair people’s lifestyle. It comprises an articular disc, that presents low regeneration capacities and the existing clinical options for repairing it are not effective. This way, it is imperative to achieve a permanent solution to guarantee a good quality of life for people who suffer from these pathologies. Complete knowledge of the unique characteristics of the disc will make it easier to achieve a successful tissue engineering (TE) construct. Thus, the search for an effective, safe and lasting solution has already started, including materials that replace the disc, is currently growing. The search for a solution based on TE approaches, which involve regenerating the disc. The present work revises the TMJ disc characteristics and its associated diseases. The different materials used for a total disc replacement are presented, highlighting the TE area. A special focus on future trends in the field and part of the solution for the TMJ problems described in this review will involve the development of a promising engineered disc approach through the use of decellularized extracellular matrices.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationTrindade D, Cordeiro R, José HC, Ângelo DF, Alves N, Moura C. Biological Treatments for Temporomandibular Joint Disc Disorders: Strategies in Tissue Engineering. Biomolecules. 2021 Jun 23;11(7):933. doi: 10.3390/biom11070933. PMID: 34201698; PMCID: PMC8301995.pt_PT
dc.identifier.doi10.3390/biom11070933pt_PT
dc.identifier.issn2218-273X
dc.identifier.urihttp://hdl.handle.net/10400.8/8379
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherMDPIpt_PT
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/pt_PT
dc.subjectDecellularizationpt_PT
dc.subjectTissue engineeringpt_PT
dc.subjectDisc dysfunctionspt_PT
dc.subjectFibrocartilagept_PT
dc.subjectTemporomandibular joint discpt_PT
dc.titleBiological Treatments for Temporomandibular Joint Disc Disorders: Strategies in Tissue Engineeringpt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.titleBiomoleculespt_PT
oaire.citation.volume11pt_PT
person.familyNameTrindade
person.familyNameCordeiro
person.familyNameÂngelo
person.familyNameAlves
person.familyNameMonteiro de Moura
person.givenNameDaniela Alexandra
person.givenNameRachel
person.givenNameDavid
person.givenNameNuno
person.givenNameCarla Sofia
person.identifierPCP-2MEAAAAJ&hl=pt-PT
person.identifier452149
person.identifier.ciencia-id6316-1507-A39A
person.identifier.ciencia-id6A15-D2F9-9962
person.identifier.ciencia-id2C1B-F1D5-5A08
person.identifier.ciencia-id311E-1559-8F6C
person.identifier.ciencia-id671C-8FEC-A14A
person.identifier.orcid0000-0003-3621-7095
person.identifier.orcid0000-0001-8217-8600
person.identifier.orcid0000-0001-8411-9946
person.identifier.orcid0000-0002-5016-0868
person.identifier.orcid0000-0003-2610-1005
person.identifier.ridN-4073-2013
person.identifier.scopus-author-id7006403383
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublicationd27807bb-1deb-4427-8a9f-e7cb5ea2c147
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relation.isAuthorOfPublication33d084bb-ac8d-454a-ac58-25be1331ce04
relation.isAuthorOfPublication.latestForDiscovery40ae14b4-0d56-4373-ba78-4fb4b88827e0

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