Publicação
PHEMA-based thin hydrogel films for biomedical applications
| dc.contributor.author | De Giglio, E. | |
| dc.contributor.author | Cafagna, D. | |
| dc.contributor.author | Giangregorio, MM | |
| dc.contributor.author | Domingos, Marco | |
| dc.contributor.author | Mattioli-Belmonte, M. | |
| dc.contributor.author | Cometa, S. | |
| dc.date.accessioned | 2025-12-03T15:02:42Z | |
| dc.date.available | 2025-12-03T15:02:42Z | |
| dc.date.issued | 2011-06-17 | |
| dc.description.abstract | Poly(2-hydroxyethyl methacrylate) based thin coatings were electro-synthesized by cyclic voltammetry on Au-coated quartz crystal surfaces to study different solid—liquid interfacial processes. By varying the electrochemical parameters and the presence or not of a crosslinking agent, films were obtained with thicknesses ranging from 5 to 90 nm. Surface characterization was performed by X-ray photoelectron spectroscopy, atomic force microscopy, and static contact angle measurements. Using quartz crystal microbalance with dissipation monitoring to investigate the relationship between the film thickness and the swelling behavior, it was found that these characteristics can be modulated by varying either the number of voltammetric cycles or the presence of the crosslinker. Cell adhesion and biocompatibility tests indicate that these film coatings were suitable for biomedical applications. | eng |
| dc.description.sponsorship | The authors thank Prof. P. Cosma of Bari University for useful discussions about electrochemical measurements. We also thank to Mr G. Cosmai for the fabrication of the crystal holder and Mr S. Giacummo, Dr A. Pedico, and Dr C. Ferretti for their technical assistance. This study was partly supported by grants to Dr De Giglio (National grant Progetto Strategico cod. CIP PS_046 ‘Studio e Sviluppo di Materiali Innovativi per Applicazioni in Chirurgia Laser della Cornea’ founded by the Apulia Region) and Dr Mattioli-Belmonte (RSA 2009, Marche Polytechnic University). | |
| dc.identifier.citation | De Giglio E, Cafagna D, Giangregorio M, Domingos M, Mattioli-Belmonte M, Cometa S. PHEMA-based thin hydrogel films for biomedical applications. Journal of Bioactive and Compatible Polymers. 2011;26(4):420-434. doi:10.1177/0883911511410460 | |
| dc.identifier.doi | 10.1177/0883911511410460 | |
| dc.identifier.issn | 0883-9115 | |
| dc.identifier.issn | 1530-8030 | |
| dc.identifier.uri | http://hdl.handle.net/10400.8/14821 | |
| dc.language.iso | eng | |
| dc.peerreviewed | yes | |
| dc.publisher | SAGE Publications | |
| dc.relation.hasversion | https://journals.sagepub.com/doi/10.1177/0883911511410460 | |
| dc.relation.ispartof | Journal of Bioactive and Compatible Polymers | |
| dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | |
| dc.subject | PHEMA-based thin films | |
| dc.subject | electro-synthesis | |
| dc.subject | film swelling | |
| dc.subject | fibroblasts | |
| dc.subject | QCM-D | |
| dc.title | PHEMA-based thin hydrogel films for biomedical applications | eng |
| dc.type | journal article | |
| dspace.entity.type | Publication | |
| oaire.citation.issue | 4 | |
| oaire.citation.title | Journal of Bioactive and Compatible Polymers | |
| oaire.citation.volume | 26 | |
| oaire.version | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |
| person.familyName | Domingos | |
| person.givenName | Marco | |
| person.identifier.ciencia-id | B512-2D06-5897 | |
| person.identifier.orcid | 0000-0002-6693-790X | |
| relation.isAuthorOfPublication | 1fb3bd4b-f499-4db6-93c1-3a671f116d07 | |
| relation.isAuthorOfPublication.latestForDiscovery | 1fb3bd4b-f499-4db6-93c1-3a671f116d07 |