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Design of tissue engineering scaffolds based on hyperbolic surfaces: Structural numerical evaluation

2014-06-13Artigo científico Acesso aberto
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datacite.subject.fosEngenharia e Tecnologia::Engenharia Médica
datacite.subject.fosEngenharia e Tecnologia::Engenharia Mecânica
datacite.subject.sdg03:Saúde de Qualidade
dc.contributor.authorAlmeida, Henrique A.
dc.contributor.authorBártolo, Paulo J.
dc.date.accessioned2026-05-08T15:00:02Z
dc.date.available2026-05-08T15:00:02Z
dc.date.issued2014-06-13
dc.description.abstractTissue engineering represents a new field aiming at developing biological substitutes to restore, maintain, or improve tissue functions. In this approach, scaffolds provide a temporary mechanical and vascular support for tissue regeneration while tissue in-growth is being formed. These scaffolds must be biocompatible, biodegradable, with appropriate porosity, pore structure and distribution, and optimal vascularization with both surface and structural compatibility. The challenge is to establish a proper balance between porosity and mechanical performance of scaffolds.This work investigates the use of two different types of triple periodic minimal surfaces, Schwarz and Schoen, in order to design better biomimetic scaffolds with high surface-to-volume ratio, high porosity and good mechanical properties. The mechanical behaviour of these structures is assessed through the finite element method software Abaqus. The effect of two parametric parameters (thickness and surface radius) is also evaluated regarding its porosity and mechanical behaviour.eng
dc.description.sponsorshipFunding text This research was supported by the Portuguese Foundation for Science and Technology through a PhD Grant ( SFRH/BD/37604/2007 ), a Strategic Project ( Pest-OE/EME/UI4044/2013 ) and a Research Project “Multimaterial microstereo-thermal-lithography (μSTLG) ” ( PTDC/EME-PME/098037/2008 ). Authors also acknowledge the support of the European Commission through the Marie Curie Project “International Research Exchange for Biomedical Devices Design and Prototyping” (IREBID).
dc.description.sponsorshipFundação para a Ciência e a Tecnologia (FCT); European Commission (Marie Curie Actions).
dc.identifier.citationAlmeida, H. A., & Bártolo, P. J. (2014). Design of tissue engineering scaffolds based on hyperbolic surfaces: Structural numerical evaluation. Medical Engineering & Physics, 36(8), 1033-1040. https://doi.org/10.1016/j.medengphy.2014.05.006
dc.identifier.doi10.1016/j.medengphy.2014.05.006
dc.identifier.issn1350-4533
dc.identifier.issn1873-4030
dc.identifier.urihttp://hdl.handle.net/10400.8/16261
dc.language.isoeng
dc.peerreviewedyes
dc.publisherElsevier
dc.relationPROJECTO INTELIGENTE DE SCAFFOLDS OBTIDOS POR PROTOTIPAGEM RÁPIDA
dc.relationStrategic Project - UI 4044 - 2013-2014
dc.relationMultimaterial microstereo-thermal-lithography (μSTLG)
dc.relation.hasversionhttps://www.sciencedirect.com/science/article/abs/pii/S1350453314001210
dc.relation.ispartofMedical Engineering & Physics
dc.rights.uriN/A
dc.subjectHyperbolic surfaces
dc.subjectNumerical simulation
dc.subjectScaffolds
dc.subjectStructural analysis
dc.subjectTissue engineering
dc.titleDesign of tissue engineering scaffolds based on hyperbolic surfaces: Structural numerical evaluationeng
dc.typejournal article
dspace.entity.typePublication
oaire.awardNumberSFRH/BD/37604/2007
oaire.awardNumberPEst-OE/EME/UI4044/2013
oaire.awardNumberPTDC/EME-PME/098037/2008
oaire.awardTitlePROJECTO INTELIGENTE DE SCAFFOLDS OBTIDOS POR PROTOTIPAGEM RÁPIDA
oaire.awardTitleStrategic Project - UI 4044 - 2013-2014
oaire.awardTitleMultimaterial microstereo-thermal-lithography (μSTLG)
oaire.awardURIhttp://hdl.handle.net/10400.8/13226
oaire.awardURIhttp://hdl.handle.net/10400.8/13452
oaire.awardURIhttp://hdl.handle.net/10400.8/13471
oaire.citation.endPage1040
oaire.citation.issue8
oaire.citation.startPage1033
oaire.citation.titleMedical Engineering & Physics
oaire.citation.volume36
oaire.fundingStreamPIDDAC
oaire.fundingStream6817 - DCRRNI ID
oaire.fundingStream5876-PPCDTI
oaire.versionhttp://purl.org/coar/version/c_970fb48d4fbd8a85
person.familyNameAlmeida
person.familyNameBartolo
person.givenNameHenrique de Amorim
person.givenNamePaulo
person.identifier46395
person.identifier203086
person.identifier.ciencia-id8F1D-4370-84BE
person.identifier.ciencia-id5810-9BF9-4522
person.identifier.orcid0000-0002-1367-2290
person.identifier.orcid0000-0003-3683-726X
person.identifier.ridD-6275-2012
person.identifier.ridF-2421-2013
person.identifier.scopus-author-id55938867800
person.identifier.scopus-author-id6603353041
relation.isAuthorOfPublicationf3bfdd6a-e959-4e13-8a20-fb1b286a3dd0
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relation.isAuthorOfPublication.latestForDiscoveryf3bfdd6a-e959-4e13-8a20-fb1b286a3dd0
relation.isProjectOfPublication69dcc61e-26de-4950-96cb-94b5db8d0484
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