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Understanding the Metabolic Syndrome Using a Biomedical Chemistry Profile

2015Book part Open access
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datacite.subject.fosCiências Médicas::Ciências da Saúde
datacite.subject.sdg03:Saúde de Qualidade
dc.contributor.authorPereira, Cidália
dc.contributor.authorMonteiro, Rosário
dc.contributor.authorMartins, Maria João
dc.date.accessioned2025-12-15T16:01:22Z
dc.date.available2025-12-15T16:01:22Z
dc.date.issued2015
dc.description.abstract2.3.1 Introduction For quite some time, it has been identified that high blood pressure, dyslipidemia [increased triglycerides and reduced high-density lipoprotein (HDL) cholesterol levels], impaired glucose homeostasis and abdominal obesity take place concurrently more than by random, supporting the existence of the metabolic syndrome (MetSyn). Additionally, hyperuricemia, a prothrombotic state, oxidative stress, chronic low grade inflammation, increased levels of apolipoprotein-B and small dense low density lipoprotein (LDL) cholesterol (contributing to atherogenic dyslipidemia), non-alcoholic fatty liver disease and/or non-alcoholic steatohepatitis, obstructive sleep apnea and/or polycystic ovarian disease (Fulop, 2006; Alberti, 2009; Roberts, 2009; Ma, 2012; Matsuda, 2013; Mule, 2014; Carson, 2015) are quite often present on the MetSyn, although not yet included in its current/actual definition. Taking this into consideration, it is not surprising that the MetSyn associates with an increased risk of type 2 diabetes mellitus (T2DM) and atherosclerotic cardiovascular disease (Fulop, 2006; Qiao, 2007; Carson, 2015).eng
dc.description.sponsorshipAcknowledgements: This work has been supported by FCT (Fundação para a Ciência e Tecnologia, PEst-OE/SAU/UI0038/2014) and Instituto de Investigação e Inovação em Saúde, University of Porto, Porto, Portugal. We thank Unicer Bebidas, S.A. (Leça do Balio, Matosinhos, Portugal) the supply of the Portuguese natural mineral-rich water tested.
dc.identifier.citationPereira, C., Monteiro, R. & João Martins, M. (2015). 2.3 Understanding the Metabolic Syndrome Using a Biomedical Chemistry Profile. In Biomedical Chemistry: Current Trends and Developments (pp. 132-147). Warsaw, Poland: De Gruyter Open Poland. https://doi.org/10.1515/9783110468755-005
dc.identifier.doi10.1515/9783110468755-005
dc.identifier.isbn978-311046875-5
dc.identifier.issn978-311046874-8
dc.identifier.urihttp://hdl.handle.net/10400.8/15057
dc.language.isoeng
dc.peerreviewedyes
dc.publisherDe Gruyter
dc.relationStrategic Project - UI 38 - 2014
dc.relation.hasversionhttps://www.degruyterbrill.com/document/doi/10.1515/9783110468755-005/html?lang=de&srsltid=AfmBOopjjb-KAvP40YR1APWWe-JULkYtsoHEsRDnutTQzzXvay2FMZRk
dc.relation.ispartofBiomedical Chemistry
dc.rights.uriN/A
dc.subjectMetabolic Syndrome
dc.titleUnderstanding the Metabolic Syndrome Using a Biomedical Chemistry Profileeng
dc.title.alternative2.3 Understanding the Metabolic Syndrome Using a Biomedical Chemistry Profileeng
dc.typebook part
dspace.entity.typePublication
oaire.awardTitleStrategic Project - UI 38 - 2014
oaire.awardURIinfo:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/PEst-OE%2FSAU%2FUI0038%2F2014/PT
oaire.citation.endPage147
oaire.citation.startPage132
oaire.citation.titleBiomedical Chemistry: Current Trends and Developments
oaire.fundingStream6817 - DCRRNI ID
oaire.versionhttp://purl.org/coar/version/c_970fb48d4fbd8a85
person.familyNamePereira
person.givenNameCidália Almeida
person.identifier.ciencia-idAC15-8934-CC03
person.identifier.orcid0000-0001-9934-9648
person.identifier.ridGPP-6411-2022
person.identifier.scopus-author-id56016000600
project.funder.identifierhttp://doi.org/10.13039/501100001871
project.funder.nameFundação para a Ciência e a Tecnologia
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relation.isAuthorOfPublication.latestForDiscoverya4dd40ab-92e7-42e2-8a47-99f2f3879b89
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