The decrease of NAD(P)H:quinone oxidoreductase 1 activity and increase of ROS production by NADPH oxidases are early biomarkers in doxorubicin cardiotoxicity

Lagoa, Ricardo; Gañán, Carlos; López-Sánchez, Carmen; García-Martínez, Virginio; Gutierrez-Merino, Carlos

http://hdl.handle.net/10400.8/2352

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Authors

Lagoa, Ricardo

Gañán, Carlos

López-Sánchez, Carmen

García-Martínez, Virginio

Gutierrez-Merino, Carlos

Keywords

Cellular bioenergetics NQO1 Cardiomyopathy Oxidative stress Anthracycline Lipid oxidation Research Subject Categories::NATURAL SCIENCES::Biology::Cell and molecular biology::Toxicology Research Subject Categories::MEDICINE::Physiology and pharmacology Research Subject Categories::MEDICINE::Morphology, cell biology, pathology Research Subject Categories::MEDICINE::Chemistry::Biochemistry