Browsing by Author "Silva, F.S."
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- 45S5 BAG-Ti6Al4V structures: The influence of the design on some of the physical and chemical interactions that drive cellular responsePublication . Melo-Fonseca, F.; Lima, R.; Costa, M.M.; Bartolomeu, F.; Alves, Nuno; Miranda, A.; Gasik, M.; Silva, F.S.; Silva, N.A.; Miranda, G.Multi-material Ti6Al4V cellular structures impregnated with 45S5 bioactive glass were designed and produced using Selective LaserMelting (SLM), an additive manufacturing technique, combinedwith Press and Sintering focusing on load bearing components like hip implants. These structures were designed to combine Ti6Al4V mechanical properties and promote bone ingrowth into the structure as the bioactive material (45S5) is being absorbed and replaced by newly formed bone. The influence of these structures design on some of the physical and chemical aspects that drive cellular response was assessed. Roughness, wettability, bioactive glass quantity and quality on the structures after processing and the pH measured during cell culture (as a consequence of bioactive glass dissolution) were evaluated and correlated with cellular viability, cellular distribution, morphology and proliferation on the surface and inside the structures.
- Additive manufacturing of NiTi-Ti6Al4V multi-material cellular structures targeting orthopedic implantsPublication . Bartolomeu, F.; Costa, M.M.; Alves, N.; Miranda, G.; Silva, F.S.The amount of hip revision surgeries is significantly increasing due to the loss of fixation between implant and bone, that leads to implant failure. The stiffness mismatch between Ti6Al4V hip implants and bone tissue, the non-uniform implant-bone contact pressure, and the poor wear resistance of Ti6Al4V are pointed as three critical issues that contribute to these implant’s failure. In this study, a multi-material design and fabrication concept was exploited aiming to change traditional manufacturing paradigms, by allocating different biomaterials in a single component targeting a multi-functional hip implant. Selective Laser Melting technology was explored to fabricate NiTi-Ti6Al4V multi-material cellular structures with a Ti6Al4V inner region and a NiTi outer region. This work was focused on the SLM fabrication and processing parameters validation on a commercial SLM equipment. The morphological analyses allowed to assess a successful solidification and bond between NiTi and Ti6Al4V materials in the transition region. The shear tests revealed a high bond strength of the transition region with an average strength of 33 MPa. The nano-indentation results showed that the Ti6Al4V region exhibits a higher hardness and elastic modulus when compared with the NiTi region. This work is a part of a broader objective that aims to create a NiTi-Ti6Al4V multi-material and cellular structured hip implant capable to provide customized stiffness, superior wear resistance and a controlled NiTi outer region volume change.
- Corrosion behaviour of PEEK or β-TCP-impregnated Ti6Al4V SLM structures targeting biomedical applicationsPublication . Costa, M.M.; Dantas, T.A.; Bartolomeu, F.; Alves, N.; Silva, F.S.; Miranda, G.; Toptan, F.Ti6Al4V cellular structures were produced by selective laser melting (SLM) and then filled either with beta-tricalcium phosphate (β-TCP) or PEEK (poly-ether-ether-ketone) through powder metallurgy techniques, to improve osteoconductivity and wear resistance. The corrosion behavior of these structures was explored considering its importance for the long-term performance of implants. Results revealed that the incorporation of open cellular pores induced higher electrochemical kinetics when being compared with dense structures. The impregnation of β-TCP and PEEK led to the creation of voids or gaps between the metallic matrix and the impregnated material which also influenced the corrosion behavior of the cellular structures.
- Development of β-TCP-Ti6Al4V structures: Driving cellular response by modulating physical and chemical propertiesPublication . Costa, M.M.; Lima, R.; Melo-Fonseca, F.; Bartolomeu, F.; Alves, N.; Miranda, A.; Gasik, M.; Silva, F.S.; Silva, N.A.; Miranda, G.Load-bearing implants success is strongly dependent on several physical and chemical properties that are known to drive cellular response. In this work, multi-material β-TCP-Ti6Al4V cellular structures were designed to combine Ti6Al4V mechanical properties and β-Tricalcium Phosphate bioactivity, in order to promote bone ingrowth as the bioactive material is being absorbed and replaced by newly formed bone. In this sense, the produced structures were characterized regarding roughness, wettability, β-TCP quantity and quality inside the structures after fabrication and the pH measured during cell culture (as consequence of β-TCP dissolution) and those aspects were correlated with cellular viability, distribution, morphology and proliferation. These structures displayed a hydrophilic behavior and results showed that the addition of β-TCP to these cellular structures led to an alkalization of the medium, aspect that significantly influences the cellular response. Higher impregnation ratios were found more adequate for lowering the media pH and toxicity, and thus enhance cell adhesion and proliferation.
- Engineering the elastic modulus of NiTi cellular structures fabricated by selective laser meltingPublication . Bartolomeu, F.; Costa, M.M.; Alves, N.; Miranda, G.; Silva, F.S.Nickel-titanium (NiTi) cellular structures are a very promising solution to some issues related to orthopaedic implant failure. These structures can be designed and fabricated to simultaneously address a combination of mechanical and physical properties, such as elastic modulus, porosity, wear and corrosion resistance, biocompatibility and appropriate biological environment. This ability can enhance the modest interaction currently existing between metallic dense implants and surrounding bone tissue, allowing long-term successful orthopaedic implants. For that purpose, NiTi cellular structures with different levels of porosity intended to reduce the elastic modulus were designed, modelled, selective laser melting (SLM) fabricated and characterized. Significant differences were found between the CAD design and the SLM-produced NiTi structures by performing systematic image analysis. This work proposes designing guidelines to anticipate and correct the systematic differences between CAD and produced structures. Compressive tests were carried out to estimate the elastic modulus of the produced structures and finite element analyses were performed, for comparison purposes. Linear correlations were found for the dimensions, porosity, and elastic modulus when comparing the CAD design with the SLM structures. The produced NiTi structures exhibit elastic moduli that match that of bone tissue, which is a good indication of the potential of these structures in orthopaedic implants.
- Implant surface design for improved implant stability: A study on Ti6Al4V dense and cellular structures produced by Selective Laser MeltingPublication . Bartolomeu, F.; Costa, M.M.; Gomes, J.R.; Alves, N.; Silva, F.S.; Miranda, G.Focusing on implant surface design, aiming to improve implant primary stability, SLM technology was explored to produce dense and cellular structured Ti6Al4V specimens. The SLM specimens and also a commercial casted/forged Ti6Al4V group, were sandblasted and acid-etched to obtain a moderate surface roughness topography, typically used in implant manufacturing. Ti6Al4V-bone interaction and tribological performance were assessed by performing sliding tests aiming to replicate in some extension the insertion of a hip implant. The results shown a 24 and 32% higher kinetic friction coefficient values when comparing the cellular structures with the conventional casted/forged Ti6Al4V. These friction results together with a high amount of adhered bone are promising evidences of a higher efficiency of Ti6Al4V cellular structures for enhancing implant stability.
- Multi-material Ti6Al4V & PEEK cellular structures produced by Selective Laser Melting and Hot Pressing: A tribocorrosion study targeting orthopedic applicationsPublication . Bartolomeu, F.; Buciumeanu, M.; Costa, M.M.; Alves, N.; Gasik, M.; Silva, F.S.; Miranda, G.Ti6Al4V-alloy is commonly used in dental and orthopedic applications where tribochemical reactions occur at material/bone interface. These reactions are one of the main concerns regarding Ti6Al4V implants due to the generation of wear particles, linked to the release of metallic ions in toxic concentration which occurs when TiO2 passive film is destroyed by means of wear and corrosion simultaneously. In the present study, a multi-material Ti6Al4V-PEEK cellular structure is proposed. Selective Laser Melting technique was used to produce Ti6Al4V dense and cellular structured specimens, whilst Hot-Pressing technique was employed to obtain multi-material Ti6Al4V-PEEK structures. This study investigates the tribocorrosion behavior of these materials under reciprocating sliding, comparing them with commercial forged Ti6Al4V. Open-circuit-potential was measured before, during and after sliding while dynamic coefficient of friction was assessed during sliding. The results showed an improved wear resistance and a lower tendency to corrosion for the multi-material Ti6Al4V-PEEK specimens when compared to dense and cellular structures mono-material specimens. This multi-material solution gathering Ti6Al4V and PEEK, besides being able to withstand the loads occurring after implantation on dental and orthopedic applications, is a promising alternative to fully dense metals once it enhances the tribocorrosion performance.
- Predicting the output dimensions, porosity and elastic modulus of additive manufactured biomaterial structures targeting orthopedic implantsPublication . Bartolomeu, F.; Fonseca, J.; Peixinho, N.; Alves, N.; Gasik, M.; Silva, F.S.; Miranda, G.SLM accuracy for fabricating porous materials is a noteworthy hindrance when aiming to obtain biomaterial cellular structures owing precise geometry, porosity, open-cells dimension and mechanical properties as outcomes. This study provides a comprehensive characterization of seventeen biomaterial Ti6Al4V-based structures in which experimental and numerical investigations (compression stress-strain tests) were carried out. Monomaterial Ti6Al4V cellular structures and multi-material Ti6Al4V-PEEK cellular structures were designed, produced by SLM and characterized targeting orthopedic implants. In this work, the differences between the CAD design and the as-produced Ti6Al4V-based structures were obtained from image analysis and were used to develop predictive models. The results showed that dimensional deviations inherent to SLM fabrication are systematically found for different dimensional ranges. The present study proposes several mathematical models, having high coefficients of determination, that estimate the real dimensions, porosity and elastic modulus of Ti6Al4V-based cellular structures as function of the CAD model. Moreover, numerical analysis was performed to estimate the octahedral shear strain for correlating with bone mechanostat theory limits. The developed models can help engineers to design and obtain near-net shape SLM biomaterials matching the desired geometry, opencells dimensions, porosity and elastic modulus. The obtained results show that by using these AM structures design it is possible to fabricate components exhibiting a strain and elastic modulus that complies with that of bone, thus being suitable for orthopedic implants.
- Predictive models for physical and mechanical properties of 316L stainless steel produced by selective laser meltingPublication . Miranda, G.; Faria, S.; Bartolomeu, F.; Pinto, Elodie; Madeira, S.; Mateus, Artur; P.Carreira; Alves, Nuno; Silva, F.S.; Carvalho, O.Selective Laser Melting (SLM) processing parameters are known to greatly influence 316L stainless steel final properties. A simple energy density calculation is insufficient for explaining mechanical and physical properties as well as microstructural characteristics, which are known to significantly influence these parts performance. In fact, parts produced by using different combinations of processing parameters, even presenting similar energy density, can display different properties. Thus, it is necessary to assess their influence as isolated parameters but also their interactions. This work presents a study on the influence of several SLM processing parameters (laser power, scanning speed and scanning spacing) on density, hardness and shear strength of 316L stainless steel. The influence of these processing parameters on the abovementioned properties is assessed by using statistical analysis. In order to find the significant main factors and their interactions, analysis of variance (ANOVA) is used. Furthermore, in order to assess the effect of the part building orientation, two different building strategies were tested. The influence of these processing parameters on shear strength, hardness and density were assessed for the two building strategies, thus resulting six different models that can be used as predictive design tools. The microstructures experimentally obtained were analyzed, discussed and correlated with the obtained models.
- Predictive models for physical and mechanical properties of Ti6Al4V produced by Selective Laser MeltingPublication . Bartolomeu, F.; Faria, S.; Carvalho, O.; Pinto, E.; Alves, Nuno; Silva, F.S.; Miranda, G.The properties of parts produced by Selective Laser Melting (SLM) are highly influenced by the processing parameters. The calculation of the energy density is not enough for justifying the mechanical and physical properties, and understand the microstructures of Ti6Al4V samples produced by SLM. In fact, samples produced with the same energy density, but with different processing parameters, present distinct properties. In this sense, it is necessary to assess the influence of processing parameters on SLM fabrication, as isolated parameters but also their interactions. This work presents a study on the influence of several SLM processing parameters (laser power, scan speed and scan spacing) on density, hardness and shear strength of Ti6Al4V samples. The influence of these processing parameters on the final properties of SLM parts was obtained by using statistical analysis. Additionality, with the drive of finding the significant main factors and their interactions, analysis of variance (ANOVA) was performed. The influence of the above mentioned processing parameters on shear strength, hardness and density resulted in three models that can be used as predictive design tools for Ti6Al4V parts produced by SLM technology. Moreover, a study on the microstructures of the Ti6Al4V samples was performed and correlated with the obtained models.