Meneses, JoãoFernandes, Sofia R.Alves, NunoPascoal-Faria, PaulaMiranda, Pedro Cavaleiro2026-04-272026-04-272021-11J. Meneses, S. R. Fernandes, N. Alves, P. Pascoal-Faria and P. C. Miranda, "Effects of Scaffold Electrical Properties on Electric Field Delivery in Bioreactors," 2021 43rd Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC), Mexico, 2021, pp. 4147-4151, doi: https://doi.org/10.1109/EMBC46164.2021.9630711.978-172811179-7978-1-7281-1180-32375-7477http://hdl.handle.net/10400.8/1620243rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2021; Conference date - 1 November 2021 - 5 November 2021; Conference code - 175446EISBN - 978-172811179-7Link de acesso ao documento - https://www.researchgate.net/publication/356939492_Effects_of_Scaffold_Electrical_Properties_on_Electric_Field_Delivery_in_BioreactorsIn tissue engineering, cell culture scaffolds have been widely used in combination with electrical stimulation to promote multiple cellular outcomes, like differentiation and proliferation. Nevertheless, the influence of scaffolds on the electric field delivered inside a bioreactor is often ignored and requires a deeper study. By performing numerical analysis in a capacitively coupled setup, this work aimed to predict the effects of the scaffold presence on the electric field, considering multiple combinations of scaffold and culture medium electrical properties. We concluded that the effect of the scaffold on the electric field in the surrounding culture medium was determined by the difference in electrical conductivity of these two materials. The numerical simulations pointed to significant variations in local electric field patterns, which could lead to different cellular outcomes and confound the interpretation of the experimental results.engHistogramsTissue engineeringElectrical stimulationConductivityNumerical simulationBiologyElectric fieldsconference paper10.1109/embc46164.2021.96307112694-0604