Yong, M.Melchels, F.Vaquette, C.Hutmacher, D.Adam, C.Domingos, M.Bártolo, P.2026-02-182026-02-182012Yong, M., Melchels, F., Vaquette, C., Hutmacher, D., & Adam, C. (2011, September). Polycaprolactone-based scaffold plus BMP-2 in a sheep thoracic spine. In Innovative Developments in Virtual and Physical Prototyping: Proceedings of the 5th International Conference on Advanced Research in Virtual and Rapid Prototyping, Leiria, Portugal, 28 September-1 October, 2011 (p. 89). CRC Press.978-041568418-7http://hdl.handle.net/10400.8/15667We report the application of a novel scaffold design in a sheep thoracic spine model for spine deformity correction. The combination of the calcium-phosphate coated polycaprolactone scaffolds with recombinant human bone morphogenic protein-2 are intended as a future bone graft substitute in ensuring the stability of bony intervertebral fusion. A solid free-form fabrication process based on melt extrusion has been utilized in the manufacturing of these scaffolds.engconference paper