Alves, CelsoPinteus, SuseteSimões, TiagoHorta, AndréSilva, JoanaTecelão, CarlaPedrosa, Rui2025-06-112025-06-112016-05-24Alves, C., Pinteus, S., Simões, T., Horta, A., Silva, J., Tecelão, C. and Pedrosa, R. (2016), Bifurcaria bifurcata: a key macro-alga as a source of bioactive compounds and functional ingredients. Int J Food Sci Technol, 51: 1638-1646. https://doi.org/10.1111/ijfs.131350950-54231365-2621http://hdl.handle.net/10400.8/13205The aim of this work was to study the proximate composition and the bioactive profile of Bifurcariabifurcata. It contains 73.31 0.69% of moisture, 8.57 0.11 g per 100 g dry weight (d.w.) of protein,5.81 0.14 g per 100 g d.w. of lipid content and 30.15 0.00 g per 100 g d.w. of ash. The polyunsatu-rated fatty acids were the most abundant fatty acid (FA), accounting for 2426.56 mg per 100 g which rep-resents 41.77% of the total FA. The methanolic fraction showed high quantity of polyphenols (220.01 0.010 phloroglucinol equivalents g 1 extract), DPPH radical reduction capacity (EC 50:58.82 lg mL 1)and oxygen radical absorbent capacity (3151.35 119.33 lmol Trolox equivalents g 1 extract). Thehighest antimicrobial effect was observed against Pseudomonas aeruginosa (11.3 1.5 mm) and Sac-charomyces cerevisiae (IC 50 :17.07 lg mL 1 ) induced by methanolic and dichloromethane fractions,respectively. Dichloromethane fraction revealed the highest antitumor activity on Caco-2 and HepG-2 cells. Bifurcaria bifurcata can be a promising source of bioactive compounds and functionalingredients.engAntimicrobial agentsantioxidant activityBioassaysFfatty acidsNatural productsNutritionSeaweedsjournal article10.1111/ijfs.13135