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Title: Feasibility of focal transcranial DC polarization with simultaneous EEG recording: preliminary assessment in healthy subjects and human epilepsy
Author: Faria, Paula
Fregni, Felipe
Sebastião, Fernando
Dias, Ana I.
Leal, Alberto
Keywords: EEG
Issue Date: Nov-2012
Publisher: Elsevier
Citation: Faria, P., Fregni, F., Sebastião, F., Dias, A. I. e Leal, A. (2012). Feasibility of focal transcranial DC polarization with simultaneous EEG recording: Preliminary assessment in healthy subjects and human epilepsy, Epilepsy & Behavior, 25(3), 417-425.
Abstract: We aimed to investigate the feasibility of an experimental system for simultaneous transcranial DC stimulation (tDCS) and EEG recording in human epilepsy. We report tolerability of this system in a cross-over controlled trial with 15 healthy subjects and preliminary effects of its use, testing repeated tDCS sessions, in two patients with drug-refractory Continuous Spike-Wave Discharges During Slow Sleep (CSWS). Our system combining continuous recording of the EEG with tDCS allows detailed evaluation of the interictal activity during the entire process. Stimulation with 1mA was well-tolerated in both healthy volunteers and patients with refractory epilepsy. The large reduction in interictal epileptiform EEG discharges in the two subjects with epilepsy supports further investigation of tDCS using this combined method of stimulation and monitoring in epilepsy. Continuous monitoring of epileptic activity throughout tDCS improves safety and allows detailed evaluation of epileptic activity changes induced by tDCS in patients.
Description: Artigo em acesso restrito. Apenas está disponível o abstract.
Peer review: yes
ISSN: 1525-5050
Appears in Collections:Artigos em revistas internacionais

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